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Active site-blocked factor IXa prevents intravascular thrombus formation in the coronary vasculature without inhibiting extravascular coagulation in a canine thrombosis model.

To assess the contribution of Factor IX/IXa, to intravascular thrombosis, a canine coronary thrombosis model was studied. Thrombus formation was initiated by applying current to a needle in the circumflex coronary artery. When 50% occlusion of the vessel developed, the current was stopped and animal...

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Detalhes bibliográficos
Main Authors: Benedict, C R, Ryan, J, Wolitzky, B, Ramos, R, Gerlach, M, Tijburg, P, Stern, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295722/
https://ncbi.nlm.nih.gov/pubmed/1939660
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