Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla.

Lithium, a widely used treatment for bipolar affective disorders, often causes nephrogenic diabetes insipidus. The effect of chronic lithium therapy on the expression of the vasopressin-regulated water channel Aquaporin-2 (AQP2) in rat kidney was examined. Membranes were prepared from inner medulla...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Marples, D, Christensen, S, Christensen, E I, Ottosen, P D, Nielsen, S
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1995
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295720/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7535800/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117863
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