Lithium-induced downregulation of aquaporin-2 water channel expression in rat kidney medulla.

Lithium, a widely used treatment for bipolar affective disorders, often causes nephrogenic diabetes insipidus. The effect of chronic lithium therapy on the expression of the vasopressin-regulated water channel Aquaporin-2 (AQP2) in rat kidney was examined. Membranes were prepared from inner medulla...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Marples, D, Christensen, S, Christensen, E I, Ottosen, P D, Nielsen, S
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1995
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7535800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117863
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