Therapeutic Antibodies Targeting CSF1 Impede Macrophage Recruitment in a Xenograft Model of Tenosynovial Giant Cell Tumor

Tenosynovial giant cell tumor is a neoplastic disease of joints that can cause severe morbidity. Recurrences are common following local therapy, and no effective medical therapy currently exists. Recent work has demonstrated that all cases overexpress macrophage colony-stimulating factor (CSF1), usu...

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Hongwei, Clarkson, Paul W., Gao, Dongxia, Pacheco, Marina, Wang, Yuzhuo, Nielsen, Torsten O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957133/
https://ncbi.nlm.nih.gov/pubmed/20981142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/174528
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