HAMSTER-TO-RAT HEART AND LIVER XENOTRANSPLANTATION WITH FK506 PLUS ANTIPROLIFERATIVE DRUGS,

Heterotopic hamster hearts transplanted to unmodified LEW rats underwent humoral rejection in 3 days. Survival was prolonged to a median of 4 days with 2 mg/kg/day FK506. As monotherapy, 15 mg/kg/day cyclophosphamide greatly prolonged graft survival—far more than could be accomplished with RS-61443,...

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Main Authors: Murase, Noriko, Starzl, Thomas E., Demetris, Anthony J., Valdivia, Luis, Tanabe, Minoru, Cramer, Donald, Makowka, Leonard
Format: Artigo
Jezik:Inglês
Izdano: 1993
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957097/
https://ncbi.nlm.nih.gov/pubmed/7682735
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