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Autocrine Interferon Priming in Macrophages but Not Dendritic Cells Results in Enhanced Cytokine and Chemokine Production after Coronavirus Infection

Coronaviruses efficiently inhibit interferon (IFN) induction in nonhematopoietic cells and conventional dendritic cells (cDC). However, IFN is produced in infected macrophages, microglia, and plasmacytoid dendritic cells (pDC). To begin to understand why IFN is produced in infected macrophages, we i...

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Detalhes bibliográficos
Main Authors: Zhou, Haixia, Zhao, Jincun, Perlman, Stanley
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957079/
https://ncbi.nlm.nih.gov/pubmed/20978536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00219-10
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