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Constitutive expression of a 92-kD gelatinase (type V collagenase) by rheumatoid synovial fibroblasts and its induction in normal human fibroblasts by inflammatory cytokines.

Synovial fibroblasts freshly isolated from the rheumatoid joint are characterized by their marked connective tissue degradative ability. This phenotype includes the ability to secrete large amounts of the matrix-degrading metalloproteinases, collagenase, and stromelysin. We have found that another a...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Asıl Yazarlar: Unemori, E N, Hibbs, M S, Amento, E P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 1991
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295696/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658048/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115480
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