Targeting Localized Immune Suppression Within the Tumor Through Repeat Cycles of Immune Cell-oncolytic Virus Combination Therapy

A major limitation to the use of immunotherapy in the treatment of cancer has been the localized immune suppressive environment within the tumor. Although there is evidence that tumor-selective (oncolytic) viruses may help to overcome this immune suppression, a primary limitation to their use has be...

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Detalhes bibliográficos
Main Authors: Thorne, Stephen H, Liang, Wenchun, Sampath, Padma, Schmidt, Tobi, Sikorski, Rachel, Beilhack, Andreas, Contag, Christopher H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956933/
https://ncbi.nlm.nih.gov/pubmed/20606649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.140
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