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Macrophages Expressing Heme Oxygenase-1 Improve Renal Function in Ischemia/Reperfusion Injury

Acute kidney injury has a high mortality and lacks specific therapies, with ischemia/reperfusion injury (IRI) being the predominant cause. Macrophages (Mφ) have been used successfully in cell therapy to deliver targeted therapeutic genes in models of inflammatory kidney disease. Heme oxygenase-1 (HO...

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Detalhes bibliográficos
Main Authors: Ferenbach, David A, Ramdas, Vasudev, Spencer, Nishrin, Marson, Lorna, Anegon, Ignacio, Hughes, Jeremy, Kluth, David C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956932/
https://ncbi.nlm.nih.gov/pubmed/20551909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.100
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