Cytokines from activated T cells induce normal endothelial cells to acquire the phenotypic and functional features of AIDS-Kaposi's sarcoma spindle cells.

Kaposi's sarcoma (KS) is a proliferative disease of vascular origin particularly frequent in HIV-1-infected homosexual men (AIDS-KS) and characterized by proliferating spindle-shaped cells, angiogenesis, and inflammatory cell infiltration. Previous work has suggested that KS spindle cells are of end...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Fiorelli, V, Gendelman, R, Samaniego, F, Markham, P D, Ensoli, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295689/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7535796/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117849
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