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Replacement of α-galactosidase A in Fabry disease: effect on fibroblast cultures compared with biopsied tissues of treated patients

The function and intracellular delivery of enzyme therapeutics for Fabry disease were studied in cultured fibroblasts and in the biopsied tissues of two male patients to show diversity of affected cells in response to treatment. In the mutant fibroblasts cultures, the final cellular level of endocyt...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Keslová-Veselíková, Jana, Hůlková, Helena, Dobrovolný, Robert, Asfaw, Befekadu, Poupětová, Helena, Berná, Linda, Sikora, Jakub, Goláň, Lubor, Ledvinová, Jana, Elleder, Milan
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer-Verlag 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956889/
https://ncbi.nlm.nih.gov/pubmed/18351385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-008-0586-9
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