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BENDAMUSTINE PHARMACOKINETIC PROFILE AND EXPOSURE-RESPONSE RELATIONSHIPS IN PATIENTS WITH INDOLENT NON-HODGKIN’S LYMPHOMA

PURPOSE: The pharmacokinetic profiles of bendamustine and active metabolites were defined in patients with rituximab-refractory, relapsed indolent B-cell non-Hodgkin’s lymphoma (NHL), and supported understanding of exposure-response relationships for efficacy and safety. METHODS: Bendamustine was ad...

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Detalhes bibliográficos
Main Authors: Owen, Joel S., Melhem, Murad, Passarell, Julie, D’Andrea, Denise, Darwish, Mona, Kahl, Bradley
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956859/
https://ncbi.nlm.nih.gov/pubmed/20140617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-010-1254-8
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