Purification of optical imaging ligand-Cybesin by high-speed counter-current chromatography

Fluorescent Cybesin (Cypate-Bombesin Peptide Analogue Conjugate) was synthesized from Indocyanine Green (ICG) and the bombesin receptor ligand as a contrast agent for detecting pancreas tumors. However, the LC–MS analysis indicated that the target compound was only a minor component in the reaction...

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Bibliografiske detaljer
Main Authors: Ma, Zhiyong, Ma, Ying, Sun, Xilin, Ye, Yunpeng, Shen, Baozhong, Chen, Xiaoyuan, Ito, Yoichiro
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956773/
https://ncbi.nlm.nih.gov/pubmed/20933483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.09.007
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