Involvement of reactive oxygen intermediates in cyclooxygenase-2 expression induced by interleukin-1, tumor necrosis factor-alpha, and lipopolysaccharide.

Reactive oxygen intermediates (ROIs) play an important role in inflammatory processes as mediators of injury and potentially in signal transduction leading to gene expression. Cyclooxygenase (COX) is a rate-limiting enzyme in prostanoid biosynthesis, and its recently cloned inducible form, COX-2, is...

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Publicado en:	J Clin Invest
Autores principales:	Feng, L, Xia, Y, Garcia, G E, Hwang, D, Wilson, C B
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Clinical Investigation 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295674/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7706475/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117842
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