Toll-like receptor 4 contributes to retinal ischemia/reperfusion injury

PURPOSE: We investigated whether retinal ischemia and inflammation produced by raising the intraocular pressure above normal systolic levels differs in mice that lack a functional toll-like receptor 4 (Tlr4) signaling pathway. METHODS: In this work we used the murine strain B6.B10ScN-Tlr4(lps-del)/J...

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Main Authors: Dvoriantchikova, Galina, Barakat, David J., Hernandez, Eleut, Shestopalov, Valery I., Ivanov, Dmitry
Format: Artigo
Jezik:Inglês
Izdano: Molecular Vision 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956702/
https://ncbi.nlm.nih.gov/pubmed/21031135
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