Hyperglycemia Induces Oxidative Stress and Impairs Axonal Transport Rates in Mice

BACKGROUND: While hyperglycemia-induced oxidative stress damages peripheral neurons, technical limitations have, in part, prevented in vivo studies to determine the effect of hyperglycemia on the neurons in the central nervous system (CNS). While olfactory dysfunction is indicated in diabetes, the e...

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Main Authors: Sharma, Ruchi, Buras, Eric, Terashima, Tomoya, Serrano, Faridis, Massaad, Cynthia A., Hu, Lingyun, Bitner, Brittany, Inoue, Taeko, Chan, Lawrence, Pautler, Robia G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956689/
https://ncbi.nlm.nih.gov/pubmed/20976160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013463
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