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Role of Ile-554 in lithium binding by the Na(+)/dicarboxylate cotransporter, NaDC1

Sodium-coupled transport of citric acid cycle intermediates, such as succinate and citrate, is mediated by the NaDC1 transporter located on the apical membrane of kidney proximal tubule and small intestine cells. Our previous study showed that transmembrane helix (TM) 11 of NaDC1 is important for so...

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Autors principals: Pajor, Ana M., Sun, Nina N.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956517/
https://ncbi.nlm.nih.gov/pubmed/20845974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100600j
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