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Development of dynamic kinetic resolution on large scale for (±)-1-phenylethylamine

Candida antarctica lipase B (CALB) and racemization catalyst 4 were combined in the dynamic kinetic resolution (DKR) of (±)-1-phenylethylamine (1). Several reaction parameters have been investigated to modify the method for application on multigram scale. A comparison of isopropyl acetate and alkyl...

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Detalhes bibliográficos
Main Authors: Thalén, Lisa K, Bäckvall, Jan-E
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956483/
https://ncbi.nlm.nih.gov/pubmed/20978623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.6.97
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