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Vaccines delivered by integration-deficient lentiviral vectors targeting dendritic cells induces strong antigen-specific immunity

We report a study of an integration-deficient lentiviral vector (IDLV) enveloped with a Sindbis virus glycoprotein mutant (SVGmu) capable of selectively binding to dendritic cells (DCs) for its potential as a vaccine carrier. The in vitro assays showed that the D64V point mutation in the catalytic d...

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Detalhes bibliográficos
Main Authors: Hu, Biliang, Dai, Bingbing, Wang, Pin
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956406/
https://ncbi.nlm.nih.gov/pubmed/20709004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.08.012
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