Thrombin-Induced Endothelin-1 Synthesis and Secretion in Retinal Pigment Epithelial Cells Is Rho Kinase Dependent

PURPOSE: The retinal pigment epithelium (RPE) is a major source for endothelin-1 (ET-1), a potent vasoactive peptide, at the outer blood–retinal barrier. Factors that regulate ET-1 synthesis at this site may help identify its normal function and its role in pathologic states accompanying retinal inj...

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Hlavní autoři: Narayan, Santosh, Prasanna, Ganesh, Tchedre, Kissaou, Krishnamoorthy, Raghu, Yorio, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2010
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956378/
https://ncbi.nlm.nih.gov/pubmed/20874501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2010.0072
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