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In Vitro Evaluation of a Targeted and Sustained Release System for Retinoblastoma Cells Using Doxorubicin as a Model Drug

PURPOSE: The objective of this study was to develop a novel folate receptor-targeted drug delivery system for retinoblastoma cells using doxorubicin (DOX) as a model drug. METHODS: Biodegradable DOX-loaded poly(d,l-lactide-co-glycolide)-poly(ethylene glycol)-folate (PLGA-PEG-FOL) micelles (DOXM) wer...

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Bibliographic Details
Main Authors: Boddu, Sai H.S., Jwala, Jwala, Chowdhury, Monica R., Mitra, Ashim K.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956377/
https://ncbi.nlm.nih.gov/pubmed/20874666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jop.2010.0048
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