Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).

The effects of increased GLUT4 (insulin-regulatable muscle/fat glucose transporter) expression on glucose homeostasis in a genetic model of non-insulin-dependent diabetes mellitus were determined by expressing a human GLUT4 transgene (hGLUT4) in diabetic C57BL/KsJ-db/db mice. A genomic hGLUT4 constr...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Gibbs, E M, Stock, J L, McCoid, S C, Stukenbrok, H A, Pessin, J E, Stevenson, R W, Milici, A J, McNeish, J D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1995
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7706456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117823
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