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Unexpected inhibition of cholesterol 7 alpha-hydroxylase by cholesterol in New Zealand white and Watanabe heritable hyperlipidemic rabbits.

We investigated the effect of cholesterol feeding on plasma cholesterol concentrations, hepatic activities and mRNA levels of HMG-CoA reductase and cholesterol 7 alpha-hydroxylase and hepatic LDL receptor function and mRNA levels in 23 New Zealand White (NZW) and 17 Watanabe heritable hyperlipidemic...

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Autors principals: Xu, G, Salen, G, Shefer, S, Ness, G C, Nguyen, L B, Parker, T S, Chen, T S, Zhao, Z, Donnelly, T M, Tint, G S
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295632/
https://ncbi.nlm.nih.gov/pubmed/7706454
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