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The Role of the CCL2/CCR2 Axis in Mouse Mast Cell Migration In Vitro and In Vivo

Tissue-resident mast cells (MCs) are important in allergic diseases. In a mouse model of allergic airways inflammation, an increase in peribronchiolar MCs was associated with increased concentrations of the chemokine CCL2 in lung lavage. MC progenitors (MCps) arising in bone marrow (BM) are recruite...

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Detalhes bibliográficos
Main Authors: Collington, Sarah J., Hallgren, Jenny, Pease, James E., Jones, Tatiana G., Rollins, Barrett J., Westwick, John, Austen, K. Frank, Williams, Timothy J., Gurish, Michael F., Weller, Charlotte L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956277/
https://ncbi.nlm.nih.gov/pubmed/20427772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904177
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