Proteolytic Inactivation of LL-37 by Karilysin, a Novel Virulence Mechanism of Tannerella forsythia

Tannerella forsythia is a gram-negative bacterium strongly associated with the development and/or progression of periodontal disease. Here, we have shown that a newly characterized matrix metalloprotease-like enzyme, referred to as karilysin, efficiently cleaved the antimicrobial peptide LL-37, sign...

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Bibliografiska uppgifter
Huvudupphovsmän: Koziel, Joanna, Karim, Aabdulkarim Y., Przybyszewska, Kornelia, Ksiazek, Miroslaw, Rapala-Kozik, Maria, Nguyen, Ky-Anh, Potempa, Jan
Materialtyp: Artigo
Språk:Inglês
Publicerad: S. Karger AG 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956017/
https://ncbi.nlm.nih.gov/pubmed/20375548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000281881
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