DNA Methylation in Pre-Diagnostic Serum Samples of Breast Cancer Cases: Results of a Nested Case-Control Study

Promoter methylation of tumor-suppressor genes is a frequent and early event in breast carcinogenesis. Paired tumor tissue and serum samples from women with breast cancer show that promoter methylation is detectable in both sample types, with good concordance. This suggests the potential for these s...

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Main Authors: Brooks, Jennifer D., Cairns, Paul, Shore, Roy E., Klein, Catherine B., Wirgin, Isaac, Afanasyeva, Yelena, Zeleniuch-Jacquotte, Anne
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956002/
https://ncbi.nlm.nih.gov/pubmed/20627767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canep.2010.05.006
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