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Peroxiredoxin 1 Stimulates Secretion of Pro-Inflammatory Cytokines by Binding to Toll-like Receptor 4

Peroxiredoxin 1 (Prx1) is an antioxidant and molecular chaperone that can be secreted from tumor cells. Prx1 is over-expressed in many cancers and elevation of Prx1 is associated with poor clinical outcome. In the current study we demonstrate that incubation of Prx1 with thioglycollate (TG)-elicited...

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Detalhes bibliográficos
Main Authors: Riddell, Jonah R., Wang, Xiang-Yang, Minderman, Hans, Gollnick, Sandra O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955897/
https://ncbi.nlm.nih.gov/pubmed/20018613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901945
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