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Novel cell-cell signaling by microglial transmembrane TNFα with implications for neuropathic pain

Neuropathic pain is accompanied by neuroimmune activation in dorsal horn of spinal cord. We have observed that in animal models this activation is characterized by increased expression of transmembrane tumor necrosis factor α (mTNFα) without release of soluble (sTNFα). Here we report that the pain-r...

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Detalhes bibliográficos
Main Authors: Zhou, Zhigang, Peng, Xiangmin, Hagshenas, Jafar, Insolera, Ryan, Fink, David J., Mata, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955857/
https://ncbi.nlm.nih.gov/pubmed/20609516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.06.017
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