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Enhanced scratching evoked by PAR-2 agonist and 5-HT but not histamine in a mouse model of chronic dry skin itch

Chronic itch is a symptom of many skin conditions and systemic disease, and it has been hypothesized that the chronic itch may result from sensitization of itch-signaling pathways. We induced experimental chronic dry skin on the rostral back of mice, and observed a significant increase in spontaneou...

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Autori principali: Akiyama, T, Iodi Carstens, M., Carstens, E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955821/
https://ncbi.nlm.nih.gov/pubmed/20709455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.07.024
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