Non-viral eNOS gene delivery and transfection with stents for the treatment of restenosis

BACKGROUND: In this study, we have examined local non-viral gene delivery, transfection, and therapeutic efficacy of endothelial nitric oxide synthase (eNOS) encoding plasmid DNA administered using coated stents in a rabbit iliac artery restenosis model. METHODS: Lipopolyplexes (LPPs) with eNOS expr...

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Hlavní autoři: Brito, Luis A, Chandrasekhar, Saradha, Little, Steven R, Amiji, Mansoor M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955648/
https://ncbi.nlm.nih.gov/pubmed/20875110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-925X-9-56
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