Irresponsiveness of two retinoblastoma cases to conservative therapy correlates with up- regulation of hERG1 channels and of the VEGF-A pathway

BACKGROUND: Treatment strategies for Retinoblastoma (RB), the most common primary intraocular tumor in children, have evolved over the past few decades and chemoreduction is currently the most popular treatment strategy. Despite success, systemic chemotherapeutic treatment has relevant toxicity, esp...

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Autors principals: Fortunato, Pina, Pillozzi, Serena, Tamburini, Angela, Pollazzi, Liliana, Franchi, Alessandro, La Torre, Agostino, Arcangeli , Annarosa
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Case Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955607/
https://ncbi.nlm.nih.gov/pubmed/20860824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-504
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