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Efficacy and safety of combined prolonged-release oxycodone and naloxone in the management of moderate/severe chronic non-malignant pain: results of a prospectively designed pooled analysis of two randomised, double-blind clinical trials

BACKGROUND: Two randomised 12-week, double-blind, parallel-group, multicenter studies comparing oxycodone PR/naloxone PR and oxycodone PR alone on symptoms of opioid-induced bowel dysfunction in patients with moderate/severe non-malignant pain have been conducted. METHODS: These studies were prospec...

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Autors principals: Löwenstein, Oliver, Leyendecker, Petra, Lux, Eberhard A, Blagden, Mark, Simpson, Karen H, Hopp, Michael, Bosse, Björn, Reimer, Karen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955588/
https://ncbi.nlm.nih.gov/pubmed/20920236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-10-12
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