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Platelet-Activating Factor Induces TLR4 Expression in Intestinal Epithelial Cells: Implication for the Pathogenesis of Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) is a leading cause of morbidity and mortality in neonatal intensive care units, however its pathogenesis is not completely understood. We have previously shown that platelet activating factor (PAF), bacteria and TLR4 are all important factors in the development of NEC...

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Bibliographic Details
Main Authors: Soliman, Antoine, Michelsen, Kathrin S., Karahashi, Hisae, Lu, Jing, Meng, Fan Jing, Qu, Xiaowu, Crother, Timothy R., Rabizadeh, Shervin, Chen, Shuang, Caplan, Michael S., Arditi, Moshe, Jilling, Tamas
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955554/
https://ncbi.nlm.nih.gov/pubmed/20976181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015044
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