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Transcriptome Analysis Revealed Unique Genes as Targets for the Anti-inflammatory Action of Activated Protein C in Human Macrophages

BACKGROUND: Activated protein C (APC) has been introduced as a therapeutic agent for treatment of patients with severe sepsis due to its unique anticoagulant and anti-inflammatory properties in the vascular system. In this study we investigated novel targets for the anti-inflammatory action of APC i...

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Detalhes bibliográficos
Main Authors: Pereira, Claudia P., Bachli, Esther B., Schaer, Dominik J., Schoedon, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955553/
https://ncbi.nlm.nih.gov/pubmed/20976180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015352
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