Cell-Penetrating Peptide Induces Leaky Fusion of Liposomes Containing Late Endosome-Specific Anionic Lipid

Cationic cell-penetrating peptides (CPPs) are a promising vehicle for the delivery of macromolecular drugs. Although many studies have indicated that CPPs enter cells by endocytosis, the mechanisms by which they cross endosomal membranes remain elusive. On the basis of experiments with liposomes, we...

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Hlavní autoři: Yang, Sung-Tae, Zaitseva, Elena, Chernomordik, Leonid V., Melikov, Kamran
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
Membrane
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955498/
https://ncbi.nlm.nih.gov/pubmed/20959093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.029
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