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Pulsed Electron Spin Resonance Resolves the Coordination Site of Cu(2+) Ions in α1-Glycine Receptor
Herein, we identify the coordination environment of Cu(2+) in the human α1-glycine receptor (GlyR). GlyRs are members of the pentameric ligand-gated ion channel superfamily (pLGIC) that mediate fast signaling at synapses. Metal ions like Zn(2+) and Cu(2+) significantly modulate the activity of pLGIC...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Biophysical Society
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955494/ https://ncbi.nlm.nih.gov/pubmed/20959090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.050 |
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