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Actin Cross-Linkers and the Shape of Stereocilia

Stereocilia are actin-based cellular protrusions essential for hearing. We propose that they are shaped by the detachment dynamics of actin cross-linkers, in particular espin. We account for experimentally observed stereocilium shapes, treadmilling velocity to length relationship, espin 1 localizati...

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Main Authors: Lenz, Martin, Prost, Jacques, Joanny, Jean-François
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955355/
https://ncbi.nlm.nih.gov/pubmed/20959082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.065
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