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Monte Carlo Simulations of Tau Proteins: Effect of Phosphorylation

We perform Monte Carlo simulations of tau proteins bound to a cylinder that mimics a microtubule (MT), and then study them in solution. Tau protein binds to a highly anionic MT surface to stabilize the cylindrical structure of MT. The negatively charged tail domain floats away from the anionic MT su...

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Bibliografiset tiedot
Päätekijät: Jho, Y.S., Zhulina, E.B., Kim, M.W., Pincus, P.A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Biophysical Society 2010
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955347/
https://ncbi.nlm.nih.gov/pubmed/20959078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.06.056
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