Electrostatic Interactions and Binding Orientation of HIV-1 Matrix Studied by Neutron Reflectivity

The N-terminal matrix (MA) domain of the HIV-1 Gag protein is responsible for binding to the plasma membrane of host cells during viral assembly. The putative membrane-binding interface of MA was previously mapped by means of mutagenesis and analysis of its trimeric crystal structure. However, the o...

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Autors principals: Nanda, Hirsh, Datta, Siddhartha A.K., Heinrich, Frank, Lösche, Mathias, Rein, Alan, Krueger, Susan, Curtis, Joseph E.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
Matèries:
Membrane
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955346/
https://ncbi.nlm.nih.gov/pubmed/20959092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.062
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