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Genetic and Pharmacologic Hydrogen Sulfide Therapy Attenuates Ischemia-Induced Heart Failure in Mice

BACKGROUND: Hydrogen sulfide (H(2)S) is an endogenous signaling molecule with potent cytoprotective effects. The present study evaluated the therapeutic potential of H(2)S in murine models of heart failure. METHODS AND RESULTS: Heart failure was induced by subjecting mice either to permanent ligatio...

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Detalhes bibliográficos
Main Authors: Calvert, John W., Elston, Marah, Nicholson, Chad K., Gundewar, Susheel, Jha, Saurabh, Elrod, John W., Ramachandran, Arun, Lefer, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955293/
https://ncbi.nlm.nih.gov/pubmed/20566952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.920991
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