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The 4-hydroxyestrone: Electron emission, formation of secondary metabolites and mechanisms of carcinogenesis

4-Hydroxyestrone (4-OHE(1)), a typical cancer-inducing metabolite, originating from 17β-estradiol (17β-E2), was chosen as a model for the studies. The aim was to get a deeper insight in the mechanisms of its ability to initiate cancer. It was found, that 4-OHE(1) can eject electrons [Formula: see te...

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Detalhes bibliográficos
Main Authors: Getoff, Nikola, Gerschpacher, Marion, Hartmann, Johannes, Huber, Johannes C., Schittl, Heike, Quint, Ruth Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955241/
https://ncbi.nlm.nih.gov/pubmed/19926488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jphotobiol.2009.10.003
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