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Strand- and site-specific DNA lesion demarcation by the xeroderma pigmentosum group D helicase

The most detrimental responses of the UV-exposed skin are triggered by cyclobutane pyrimidine dimers (CPDs). Although placental mammals rely solely on nucleotide excision repair (NER) to eliminate CPDs, none of the core NER factors are apparently able to distinguish this hazardous lesion from native...

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Detalhes bibliográficos
Main Authors: Mathieu, Nadine, Kaczmarek, Nina, Naegeli, Hanspeter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955138/
https://ncbi.nlm.nih.gov/pubmed/20876134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004339107
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