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Molecular evolution and the role of oxidative stress in the expansion and functional diversification of cytosolic glutathione transferases

BACKGROUND: Cytosolic glutathione transferases (cGST) are a large group of ubiquitous enzymes involved in detoxification and are well known for their undesired side effects during chemotherapy. In this work we have performed thorough phylogenetic analyses to understand the various aspects of the evo...

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Main Authors: da Fonseca, Rute R, Johnson, Warren E, O'Brien, Stephen J, Vasconcelos, Vítor, Antunes, Agostinho
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955027/
https://ncbi.nlm.nih.gov/pubmed/20843339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-281
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