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Metabolism of prostaglandin F2 alpha in Zellweger syndrome. Peroxisomal beta-oxidation is a major importance for in vivo degradation of prostaglandins in humans.

We have recently shown in vitro that the peroxisomal fraction of a rat liver homogenate has the highest capacity to beta-oxidize prostaglandins. In order to evaluate the relative importance of peroxisomes for this conversion also in vivo, we administered [3H]prostaglandin F2 alpha to an infant suffe...

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Pubblicato in:J Clin Invest
Autori principali: Diczfalusy, U, Kase, B F, Alexson, S E, Björkhem, I
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1885782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115401
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