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Gene transfer into the airway epithelium of animals by targeting the polymeric immunoglobulin receptor.

Genes of interest can be targeted specifically to respiratory epithelial cells in intact animals with high efficiency by exploiting the receptor-mediated endocytosis of the polymeric immunoglobulin receptor. A DNA carrier, consisting of the Fab portion of polyclonal antibodies raised against rat sec...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Ferkol, T, Perales, J C, Eckman, E, Kaetzel, C S, Hanson, R W, Davis, P B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295497/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7860731/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117690
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