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Linoleic acid suppresses colorectal cancer cell growth by inducing oxidant stress and mitochondrial dysfunction

Some polyunsaturated fatty acids (PUFAs), if not all, have been shown to have tumoricidal action, but their exact mechanism(s) of action is not clear. In the present study, we observed that n-6 PUFA linoleic acid (LA) inhibited tumor cell growth at high concentrations (above 300 μM); while low conce...

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Detalhes bibliográficos
Main Authors: Lu, Xiaofeng, Yu, Haining, Ma, Qi, Shen, Shengrong, Das, Undurti N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954911/
https://ncbi.nlm.nih.gov/pubmed/20868498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-9-106
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