MHC Class I Bound to an Immunodominant Theileria parva Epitope Demonstrates Unconventional Presentation to T Cell Receptors

T cell receptor (TCR) recognition of peptide-MHC class I (pMHC) complexes is a crucial event in the adaptive immune response to pathogens. Peptide epitopes often display a strong dominance hierarchy, resulting in focusing of the response on a limited number of the most dominant epitopes. Such T cell...

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Main Authors: Macdonald, Isabel K., Harkiolaki, Maria, Hunt, Lawrence, Connelley, Timothy, Carroll, A. Victoria, MacHugh, Niall D., Graham, Simon P., Jones, E. Yvonne, Morrison, W. Ivan, Flower, Darren R., Ellis, Shirley A.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954893/
https://ncbi.nlm.nih.gov/pubmed/20976198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001149
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