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Fragile X and autism: Intertwined at the molecular level leading to targeted treatments

Fragile X syndrome (FXS) is caused by an expanded CGG repeat (> 200 repeats) in the 5' untranslated portion of the fragile mental retardation 1 gene (FMR1), leading to deficiency or absence of the FMR1 protein (FMRP). FMRP is an RNA carrier protein that controls the translation of several ot...

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Detalhes bibliográficos
Main Authors: Hagerman, Randi, Hoem, Gry, Hagerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954865/
https://ncbi.nlm.nih.gov/pubmed/20858229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2392-1-12
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