Specific inhibition of eIF-5A and collagen hydroxylation by a single agent. Antiproliferative and fibrosuppressive effects on smooth muscle cells from human coronary arteries.

Restenosis occurs in 35% of patients within months after balloon angioplasty, due to a fibroproliferative response to vascular injury. These studies describe a combined fibrosuppressive/antiproliferative strategy on smooth muscle cells cultured from human primary atherosclerotic and restenotic coron...

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Autori principali: McCaffrey, T A, Pomerantz, K B, Sanborn, T A, Spokojny, A M, Du, B, Park, M H, Folk, J E, Lamberg, A, Kivirikko, K I, Falcone, D J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC295486/
https://ncbi.nlm.nih.gov/pubmed/7860726
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