Early Production of IL-22 but Not IL-17 by Peripheral Blood Mononuclear Cells Exposed to live Borrelia burgdorferi: The Role of Monocytes and Interleukin-1

If insufficiently treated, Lyme borreliosis can evolve into an inflammatory disorder affecting skin, joints, and the CNS. Early innate immunity may determine host responses targeting infection. Thus, we sought to characterize the immediate cytokine storm associated with exposure of PBMC to moderate...

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Detalhes bibliográficos
Main Authors: Bachmann, Malte, Horn, Katharina, Rudloff, Ina, Goren, Itamar, Holdener, Martin, Christen, Urs, Darsow, Nicole, Hunfeld, Klaus-Peter, Koehl, Ulrike, Kind, Peter, Pfeilschifter, Josef, Kraiczy, Peter, Mühl, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954834/
https://ncbi.nlm.nih.gov/pubmed/20976193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001144
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