Effects of combined administration of FK 506 and the purine biosynthesis inhibitors mizoribine or mycophenolic acid on lymphocyte DNA synthesis and T cell activation molecule expression in human mixed lymphocyte cultures

Our objective was to obtain new information on the in vitro antilymphocytic action of the cytokine synthesis inhibitor FK 506 and the purine biosynthesis inhibitors mycophenolic acid (MPA; the active moiety of RS61443) and mizoribine (MZB) when used alone or in combination. When added at the initiat...

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Bibliographic Details
Main Authors: Thomson, AW, Woo, J, Yao, GZ, Todo, S, Starzl, TE, Zeevi, A
Format: Artigo
Language:Inglês
Published: 1993
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954626/
https://ncbi.nlm.nih.gov/pubmed/7521738
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